In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements.
You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Fluticasone and Salmeterol Oral Inhalation pronounced as floo tik' a sone sal me' te role. Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication?
Brand names. Other uses for this medicine. What special precautions should I follow? Before using fluticasone and salmeterol oral inhalation, tell your doctor and pharmacist if you are allergic to fluticasone Flonase, Flovent , salmeterol Serevent , any other medications, milk protein, any foods, or any of the ingredients in fluticasone and salmeterol oral inhalation. Ask your pharmacist or check the Patient Information for a list of the ingredients.
These medications should not be used with fluticasone and salmeterol inhalation. Your doctor will tell you which medication you should use and which medication you should stop using. Be sure to mention any of the following: certain antifungals such as itraconazole Onmel, Sporanox and ketoconazole; beta-blockers such as atenolol Tenormin , labetalol Trandate , metoprolol Lopressor, Toprol XL , nadolol Corgard , and propranolol Inderal ; clarithromycin Biaxin, in Prevpac ; diuretics 'water pills' ; HIV protease inhibitors such as atazanavir Reyataz , indinavir Crixivan , nelfinavir Viracept , ritonavir Norvir , and saquinavir Invirase ; other medications for asthma or COPD; medications for seizures; metronidazole Flagyl ; nefazodone; and telithromycin Ketek; no longer available in U.
If you have asthma or COPD and also have allergies, talk with your doctor about ways to relieve your allergy symptoms. If your child needs to take Advair, their doctor will monitor their growth closely.
This can help lower the risk of slowing their growth. Before taking Advair, talk with your doctor about your health history. Advair may not be right for you if you have certain medical conditions or other factors affecting your health. These include:. When you get Advair from the pharmacy, the pharmacist will add an expiration date to the label on the bottle.
This date is typically 1 year from the date they dispensed the medication. The expiration date helps guarantee the effectiveness of the medication during this time. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. How long a medication remains good can depend on many factors, including how and where you store the medication.
They should be stored in their packaging and away from light. Advair HFA should not be stored near high temperatures because it can burst if it gets too hot.
This helps prevent others, including children and pets, from taking the drug by accident. It also helps keep the drug from harming the environment. The FDA website provides several useful tips on medication disposal. You can also ask your pharmacist for information on how to dispose of your medication.
Fluticasone propionate is a corticosteroid that improves asthma and COPD symptoms by reducing inflammation. It does this by binding to glucocorticoid receptors and reducing the activation and activity of immune system cells and mediators. It also inhibits mediator release from mast cells, reducing inflammation.
Salmeterol works by binding to beta2-adrenoreceptors and increasing cyclic AMP levels, prompting smooth muscle relaxation in the lungs.
Following inhalation, absolute bioavailability of fluticasone propionate is about 5. Very low levels of salmeterol reach systemic circulation. Peak concentration achieved within 0. Fluticasone propionate and salmeterol are both metabolized via the CYP3A4 pathway. Fluticasone propionate is primarily excreted via fecal route. Terminal half-life for both drugs is about 5. Advair Diskus is contraindicated as primary treatment of status asthmaticus or acute episodes of asthma or COPD that require intense treatment.
Advair HFA is contraindicated as primary treatment of status asthmaticus or acute episodes of asthma that require intense treatment. Advair Diskus and Advair HFA are both contraindicated in people with a history of hypersensitivity to their respective active and inactive ingredients including milk proteins in Advair Diskus.
Protect Advair HFA from extreme heat, as the device can burst. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Homeopathy is a popular, traditional remedy for asthma. In this article, we look at the evidence for the safety and effectiveness of homeopathic…. Regular exercise can help improve asthma symptoms in the long term.
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Learn how alcohol use can affect asthma and how to lower the chances of an attack. Medically reviewed by Dena Westphalen, Pharm. What is Advair? Advair uses. Advair side effects. Advair generic. Advair dosage. Alternatives to Advair. Advair vs. How to use Advair. Advair use with other drugs.
Advair and alcohol. Advair interactions. Advair cost. Advair and pregnancy. Advair and birth control. Advair and breastfeeding. Advair overdose. How Advair works. Common questions about Advair. Advair precautions. Advair expiration, storage, and disposal. Professional information for Advair. Latest news Could 'cupping' technique boost vaccine delivery?
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For the treatment of COPD the most common side effects are pneumonia, oral candidiasis, throat irritation, hoarse voice or trouble speaking dysphonia , viral respiratory infections, headaches and musculoskeletal pain. The FDA continues to advance new policies to promote more generic competition for complex drugs. Recently, the FDA issued 27 guidance documents to help advance the development of generic transdermal and topical delivery systems. The agency also intends to issue an umbrella guidance to help generic drug developers address some of the most challenging regulatory and scientific issues that may be encountered during the development of complex drugs.
The FDA, an agency within the U. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. Advair is available in brand and generic ; the brand is also made by GSK. Mylan makes a branded generic a generic drug with a proprietary name , called Wixela Inhub. Breo and Advair are powder inhalers , meaning that the contents of a capsule are inhaled.
Advair HFA is a metered-dose inhaler. Breo and Advair have many similarities, but also some notable differences. Many patients suffer from COPD or severe asthma, with symptoms such as wheezing and shortness of breath occurring during asthma attacks. Breo What is Breo? It can be used in patients 18 years and older. Advair What is Advair? It can be used in patients four years and older. In a six-month randomized, placebo-controlled study comparing Breo to Advair in asthma patients, both treatment groups experienced equivalent improvements in FEV1 forced expiratory volume; a measure of how much air can be exhaled in one second after a deep inhalation , quality of life scores, and asthma control scores.
There were no differences in exacerbation rates, and both drugs were well-tolerated. At the end of the week study, the researchers concluded that both drugs resulted in similar clinical improvements and both drugs have similar safety profiles. Breo and Advair are usually covered by insurance as well as Medicare Part D.
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